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CIOMS R factor from ALT, ALP, and laboratory ULNs (Bénichou 1990). R = (ALT/ALT_ULN)/(ALP/ALP_ULN), rounded to 1 decimal, then hepatocellular (R ≥ 5), cholestatic (R ≤ 2), or mixed (2 < R < 5). Deterministic published arithmetic with citation. Not a medical device, not a DILI diagnosis or RUCAM score; magent does not assay enzymes. R is the enzyme pattern only.

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